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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCX All Species: 7.88
Human Site: Y186 Identified Species: 24.76
UniProt: O43602 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.29
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43602 NP_000546.2 441 49318 Y186 P Q G V R Y I Y T I D G S R K
Chimpanzee Pan troglodytes XP_529107 435 48278 T181 Q G V R Y I Y T I D G S R K I
Rhesus Macaque Macaca mulatta XP_001100519 441 49265 Y186 P Q G V R Y I Y T I D G S R K
Dog Lupus familis XP_853182 417 46576 S172 D G S R K I G S M D E L E E G
Cat Felis silvestris
Mouse Mus musculus O88809 366 40594 E121 G S M D E L E E G E S Y V C S
Rat Rattus norvegicus Q9ESI7 365 40541 E120 I G S M D E L E E G E S Y V C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511397 792 88039 V436 N D G P G E E V L E E G F Q V
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7PLI7 748 82953 Y210 P G A V R T I Y N L C G K K I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85 99.3 85.9 N.A. 81.1 81.1 N.A. 36.3 N.A. N.A. N.A. N.A. 22.7 N.A. N.A. N.A.
Protein Similarity: 100 87.9 99.5 87.9 N.A. 81.1 81.1 N.A. 43 N.A. N.A. N.A. N.A. 37.2 N.A. N.A. N.A.
P-Site Identity: 100 0 100 0 N.A. 0 0 N.A. 13.3 N.A. N.A. N.A. N.A. 40 N.A. N.A. N.A.
P-Site Similarity: 100 6.6 100 13.3 N.A. 0 20 N.A. 26.6 N.A. N.A. N.A. N.A. 53.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 13 0 0 13 13 % C
% Asp: 13 13 0 13 13 0 0 0 0 25 25 0 0 0 0 % D
% Glu: 0 0 0 0 13 25 25 25 13 25 38 0 13 13 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 0 % F
% Gly: 13 50 38 0 13 0 13 0 13 13 13 50 0 0 13 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 13 0 0 0 0 25 38 0 13 25 0 0 0 0 25 % I
% Lys: 0 0 0 0 13 0 0 0 0 0 0 0 13 25 25 % K
% Leu: 0 0 0 0 0 13 13 0 13 13 0 13 0 0 0 % L
% Met: 0 0 13 13 0 0 0 0 13 0 0 0 0 0 0 % M
% Asn: 13 0 0 0 0 0 0 0 13 0 0 0 0 0 0 % N
% Pro: 38 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 13 25 0 0 0 0 0 0 0 0 0 0 0 13 0 % Q
% Arg: 0 0 0 25 38 0 0 0 0 0 0 0 13 25 0 % R
% Ser: 0 13 25 0 0 0 0 13 0 0 13 25 25 0 13 % S
% Thr: 0 0 0 0 0 13 0 13 25 0 0 0 0 0 0 % T
% Val: 0 0 13 38 0 0 0 13 0 0 0 0 13 13 13 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 13 25 13 38 0 0 0 13 13 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _